OUR NANOPARTICLE MANUFACTURING SYSTEMS
TAMARA
Plug and play nanoparticle synthesis with microfluidics
The simplest way to get access to the most advanced nanoparticle synthesis technology for easy control of your LNP, Liposomes, SLN PLGA nanoparticle... characteristics
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Easy and quick
Setup, run and collect your nanoparticles in less than 2 minutes
Size, PDI and EE% control
Get access to the most advanced microfluidic technology for the optimal control of your nanoparticle characteristics including size, PDI, encapsulation efficiency...
Reusable chips
Be sustainable and save money by using the same equipment for multiple batches; simply clean between runs.
From screening to in vivo
Use the same system to produce identical nanoparticle from your discovery stage (200µL) to your in vivo testings (up to 10mL/batch)
Discover TAMARA
The most accessible nanoparticle synthesis platform
RNA & DNA
Use the TAMARA platform to formulate tailored lipid nanoparticles (LNP) to effectively deliver mRNA, siRNA, tRNA, DNA, miRNA... to their target cells or organs
Small drugs
Whether it is in PLGA nanoparticles, SLN, LNP, or liposomes, use the TAMARA platform to encapsulate your active pharmaceutical ingredient (API) within a nanoparticle, ensuring precise delivery to the right location.
ASO
Close cousins to RNA & DNA, Antisense Oligonucleotides (ASO) can also be delivered using the LNP produced with TAMARA.
Diagnostic/ Theranostic
The versatility of the lipid or polymer-based nanoparticles synthesized by TAMARA extend beyond drug/RNA delivery, including applications in diagnostics and the potential for combining these capabilities in theranostics.
FEATURES
Wide range of nanoparticle types
One platform for all: TAMARA allows for the synthesis of most polymeric and lipid-based nanoparticles (RNA-LNP, liposome, PLGA…) within one single platform.
Solvent compatibility: Use most polar solvents (Ethanol, Methanol...) for the synthesis of your nanoparticles.
The best of microfluidics, for the best performances
Optimal size control: Effortlessly reach your target nanoparticle size by tuning your synthesis parameters using our user friendly features.
Best Polydispersity Idex (PDI): Get access to the most advanced microfluidics technology to achieve the most homogenous nanoparticle populations.
Nanoparticle formulation with microfluidic has never been this easy
Intuitive operation: Synthesize your nanoparticle in less than 2 minutes with the TAMARA platform. Simply set your formulation parameters, load your sample, and press on run!
You can also save your synthesis parameters for your next runs
Chip & reservoir cleaning: Easily clean your chip and reservoirs to reuse them for multiple runs!
Maximized encapsulation efficiency
Achieve the highest EE%: Employing state-of-the-art microfluidic technology, the TAMARA platform permits to reach encapsulation efficiency as high as 97% with RNA-LNP!
Payload flexibility: What is true for RNA-LNP (siRNA, mRNA, miRNA...) is also true for a wide majority of payloads including DNA, CRISPR/CAS9, small molecules, peptides, drugs...
A unique platform, from screening to preclinical
Scalability: Use the same platform to synthesis nanoparticles from 0.2 to 10 mL* while minimizing your reagent consumption by using 100% of your material.
*Accuracy & repeatability are ensured in the 0.5 to 5 mL range.
Batch-to-batch repeatability: Reach the same nanoparticle characteristics at every batch to ensure the optimal repeatability of your experiments
I am looking to test if my RNA strand can be encapsulated into LNP
Perfect for newcomers to the nanoparticle and/or microfluidic field, the TAMARA platform will allow you to easily and quickly synthesize your nanoparticles, even without experience
I want to optimize my screening process
The TAMARA platform allows for very low volume synthesis (0.2 mL) and cleaning in less than 2 minutes, allowing you to synthesize and test 100s of samples a day.
I am looking to improve the quality and reproducibility of my nanoparticles
By using the same system from screening (down to 0.2µL) to preclinical tests (10mL batches), you optimize your chances of success as you are sure to maintain your nanoparticle characteristics identical all along your development process.
We are positively impressed with the Inside Therapeutics solutions. They provided us with detailed instructions to set up the equipment, which made the system quick and easy to start. We found the equipment very user-friendly and the entire experience was highly reproducible. We were able to consistently produce lipid nanoparticles with encapsulated siRNA for drug delivery applications, with precise control of the physicochemical characteristics of the nanoparticles