OUR NANOPARTICLE MANUFACTURING SYSTEMS
TAMARA
The only plug and play nanoparticle formulation system with microfluidics that covers all R&D stages
- Quick & Intuitive
Run your sample in under 2 minutes, even without prior experience - All-in-one R&D System
Seamlessly transition from screening (0.2 mL) to in-vivo studies (30 mL) using one system. - Microfluidic Technology
Achieve optimal control over formulation conditions, to ensure ultimate repeatability and precise tuning of nanoparticle characteristic. - Reusable Chips
Designed for reusability and easy cleaning. - Maximized Reagent usage and Yield
Maximize the usage of your expensive API with virtually no losses
Check our video below to learn how to streamline your RNA-LNP and nanomedicine research with TAMARA.
They trust us & speak about us
We’ve set up TAMARA and performed our first mock run. I’m absolutely blown away by how user friendly, efficient and straight to the point this system is!
Lipid Nanoparticle/LNP
Utilize the TAMARA system to formulate customized lipid nanoparticles (LNP) for the effective delivery of mRNA, siRNA, tRNA, DNA, saRNA, or ASO to target cells or organs.
Liposomes & SLN
With nanoprecipitation technology, the TAMARA system can synthesize most types of lipid-based nanoparticles, including liposomes and SLNs.
Polymeric Nanoparticles
The flexibility of the TAMARA platform also allows for the synthesis of a wide range of polymeric nanoparticles, such as PLGA, polystyrene, and hybrid nanoparticles.
And more nanoparticles
Beyond polymer and lipid-based nanoparticles, the TAMARA platform is versatile enough to produce protein nanoparticles, nanoemulsions, and more.
Discover TAMARA
The most accessible nanoparticle synthesis platform
Easy and quick
Setup, run and collect your nanoparticles in less than 2 minutes, even as a begginer
Size, PDI and EE% control
Get access to the most advanced microfluidic technology for the optimal control of your nanoparticle characteristics including size, PDI, encapsulation efficiency...
Chips cleaning
Be sustainable and save money by cleaning your chips between runs, allowing you to reuse them!
All your R&D development with one system
Use the same system to streamline your development by formulating identical nanoparticle from your discovery stage (200µL) to your in vivo testings (up to 30mL/batch)
Maximized sample usage
With its optimized fluidic design, TAMARA maximizes the usage of your expensive API/RNA material with near 0 losses
FEATURES
Nanoparticle formulation with microfluidic has never been this easy
Intuitive operation: Synthesize your nanoparticle in less than 2 minutes with the TAMARA platform. Simply set your formulation parameters, load your sample, and press on run!
You can also save your synthesis parameters for your next runs
Chip & reservoir cleaning: Easily clean your chip and reservoirs!*
*Note: The guaranteed outcome is for the first run only. Chip's reusability depends on formulation and target volume.
A single platform for all your R&D development scales
Scalability: Utilize the same platform for all your screening, in-vitro, and in-vivo tests with our nanoparticle formulation system, covering volumes from 0.2 to 30 mL. *
*Optimal efficiency range 0,5 to 5 mL
Batch-to-Batch Consistency: Achieve consistent nanoparticle characteristics with every batch, ensuring optimal repeatability for your experiments.
Maximize Reagent Efficiency: Our near-zero loss system maximizes reagent consumption, reducing waste and optimizing your resources.
The best of microfluidics, for the best in vitro & in vivo performances
Excellent Transfection performance: Formulating RNA-LNP with TAMARA allows to achieve optimal transfection efficiency performance
State of the art cell expression: When it comes to cell expression, LNP formulated with TAMARA system consistently outperform LNP formulated with mainstream toroidal mixers
2 microfluidic mixer for maximum flexibility
Optimal size control: Effortlessly reach your target nanoparticle size by tuning your synthesis parameters using our user friendly features.
Best Polydispersity Idex (PDI): Get access to the most advanced microfluidics technology to achieve the most homogenous nanoparticle populations.
Maximize your encapsulation
Achieve the highest EE%: Employing state-of-the-art microfluidic technology, the TAMARA platform permits to reach encapsulation efficiency as high as 97% with RNA-LNP
Enhance your API utilization with excellent encapsulation yield: TAMARA offers exceptional yield levels, maximizing the effectiveness of your sample usage.
Payload flexibility: What is true for RNA-LNP (siRNA, mRNA, miRNA...) is also true for a wide majority of payloads including DNA, CRISPR/CAS9, small molecules, peptides, drugs...
Wide range of nanoparticle types
One platform for all: TAMARA allows for the synthesis of most polymeric and lipid-based nanoparticles (RNA-LNP, liposome, PLGA…) within one single platform.
Solvent compatibility: Use most polar solvents (Ethanol, Methanol...) for the synthesis of your nanoparticles.
TAMARA Specifications
TAMARA Specifications
Related Documentation
TAMARA User Manual: Download TAMARA User Manual
TAMARA Application Note: Liposomes synthesis and size characterization with high precision DLS
I am looking to test if my RNA strand can be encapsulated into LNP
Perfect for newcomers to the nanoparticle and/or microfluidic field, the TAMARA platform will allow you to easily and quickly synthesize your nanoparticles, even without prior experience at every step of your R&D process.
I want to optimize my screening process
The TAMARA platform allows for very low volume synthesis (0.2 mL) and cleaning in less than 2 minutes, allowing you to synthesize and test 10s of samples a day.
I am looking to improve the quality and reproducibility of my nanoparticles
By using the same system from screening (down to 0.2µL) to preclinical tests (10mL batches), you optimize your chances of success as you are sure to maintain your nanoparticle characteristics identical all along your development process.
We are positively impressed with the Inside Therapeutics solutions. They provided us with detailed instructions to set up the equipment, which made the system quick and easy to start. We found the equipment very user-friendly and the entire experience was highly reproducible. We were able to consistently produce lipid nanoparticles with encapsulated siRNA for drug delivery applications, with precise control of the physicochemical characteristics of the nanoparticles