OUR NANOPARTICLE MANUFACTURING SYSTEMS
TAMARA
The only plug and play nanoparticle & LNP formulation system with microfluidics that covers all your development requirements
- Quick & Intuitive
Run your sample in under 2 minutes, even without prior experience - All-in-one R&D System
Seamlessly transition from screening (0.2 mL) to in-vivo studies (30 mL) within a single platform within a single platform. - Precision Microfluidics
Achieve optimal control over formulation conditions, to ensure ultimate repeatability and precise tuning of nanoparticle characteristic. - Reusable Chips
Designed for easy cleaning and reusability - Zero-Formulation-Waste
TAMARA eliminates pre- and post-formulation waste, a feature that saves precious materials and significantly reduces operational costs.
Check our video below to learn how to streamline your RNA-LNP and nanomedicine research with TAMARA.
They trust us & speak about us
"Our laboratory has been utilizing the TAMARA microfluidic device for nanoparticle preparation, which has enhanced our research capabilities. The microfluidic device offers an adequate combination of precision, scalability, and usability that sets it apart."
"We’ve set up TAMARA and performed our first mock run. I’m absolutely blown away by how user friendly, efficient and straight to the point this system is! "
Lipid Nanoparticle/RNA-LNP
Formulate any types of lipid nanoparticles (LNP) using TAMARA for the effective delivery of mRNA, siRNA, tRNA, DNA, saRNA, or ASO to target cells or organs.
Liposomes & SLN
With its optimized nanoprecipitation & self-assembly process control, the TAMARA system enables the efficient synthesis of a wide variety of lipid-based nanoparticles, including liposomes and SLNs.
Polymeric Nanoparticles
The flexibility of the TAMARA platform also allows for the synthesis of a wide range of polymeric nanoparticles, such as PLGA, polystyrene, and hybrid nanoparticles.
And next-gen nanoparticles
Beyond polymer- and lipid-based nanoparticles, TAMARA's versatility allows it to produce protein and peptide nanoparticles...
It also enables precise functionalization, enhancing selectivity and targeting through the conjugation of ligands, peptides...
Discover TAMARA
The most accessible nanoparticle synthesis platform
What makes TAMARA unique?
Easy and quick
Setup, run and collect your nanoparticles in less than 2 minutes, even as a begginer. Cleaning is just as quick with TAMARA’s integrated cleaning protocol.
The only LNP formulation system for all your R&D
Unlike other approches that require two separate platforms, TAMARA is the only platform that enables nanoparticle formulation across all R&D stages, from low-volume screening (200µL) to in vivo-scale production (30mL per batch), all within the same system.
This ensures unmatched consistency, saves time, and reduces costs—streamlining your entire development process.
Ultimate Size, PDI and EE% control
Get access to the most advanced microfluidic technology for the optimal control of your nanoparticle characteristics including size, PDI, encapsulation efficiency...
Chips reusability
Be sustainable and save money by cleaning your chips between runs, allowing you to reuse them!
Zero-formulation waste
Thanks to its unique optimized fluidic design, TAMARA eliminates your head & tail to avoid any reagents losses and reach near 100% encapsulation yield of your expensive API/RNA
FEATURES
Nanoparticle/RNA-LNP formulation with microfluidic made easy
Effortless and Intuitive Operation
Formulating nanoparticles has never been easier. With the TAMARA platform, you can synthesize nanoparticles in less than a minute, even with no previous experience.
Just set your formulation parameters, load your sample, and press "Run" — it’s that simple!
Hassle-free cleaning
Using the integrated cleaning protocol, easily clean your chip and reservoirs to reuse them multiple times!*
*Note: The guaranteed outcome is for the first run only. Chip's reusability depends on formulation and target volume.


A single platform for all your R&D development scales
Comprehensive R&D system
One of TAMARA unique features lies in that fact that contrary to its competitors, you can use the same system to streamline your development by formulating identical nanoparticle from your screening stage (200µL) to your in vivo testings (up to 30mL/batch) where they instead use 2*
*Optimal efficiency range 0,5 to 5 mL
Batch-to-Batch Consistency
Achieve consistent nanoparticle characteristics with every batch, ensuring optimal repeatability for your experiments.
Maximize RNA/API recovery
Our advanced fluidic design eliminates head and tail losses, optimizing reagent usage. This ensures maximum recovery, minimizes waste, and enhances the potency of your formulations!
Our users say it better:
"TAMARA accommodates a broad range of applications, from small-scale screening (batch sizes below 500 microliters) to larger-scale production for in vivo studies requiring higher volumes. This versatility makes it an important tool for our diverse projects."
The best of microfluidics for the best in vitro & in vivo performances
State of the art Transfection performance
Formulating RNA-LNP with TAMARA allows to achieve optimal potency
Ultimate cell expression
When it comes to protein expression, RNA-LNP formulated with TAMARA system consistently outperform RNA-LNP formulated with other mainstream approches.


Two microfluidic mixer for maximum flexibility
Optimal size control & flexibility
Each chip features two idependant microfluidic designs head to toe —Baffle and Herringbone—providing unparalleled flexibility in tailoring nanoparticle characteristics. Fine-tune results further using formulation parameters such as Total Flow Rate (TFR) and Flow Rate Ratio (FRR).
Best Polydispersity Idex (PDI)
Get access to the most advanced microfluidics technology to achieve the most homogenous nanoparticle populations.
Maximize your encapsulation
State-of-the-art Encapsulation Efficiency
Embedding advanced microfluidic technology, TAMARA achieves encapsulation efficiencies as high as 98% for RNA-LNPs.
Unmatched RNA recovery
Thanks to its innovative microfluidic fluidic design with no head & tail, the TAMARA platform allowing for sample recovery exceeding 95% for RNA-LNPs, ensuring maximum recovery of your valuable and costly reagents.


Versatile Nanoparticle Synthesis
TAMARA enables the synthesis of a wide range of polymeric and lipid-based nanoparticles (e.g., RNA-LNP, liposomes, PLGA) on a single platform, seamlessly adapting to diverse payloads such as RNA (siRNA, mRNA, miRNA), DNA, CRISPR/Cas9, proteins, peptides, and small molecules.
TAMARA can also be used for the next generation of nanoparticle requiring decoration with ligands, peptides... for more precise targeting.
Broad Solvent Compatibility
Compatible with most polar solvents, including ethanol, methanol, acetonitrile... TAMARA ensures flexibility for a variety of nanoparticle formulations.
TAMARA Specifications

TAMARA Specifications
Related Documentation
TAMARA User Manual: Download TAMARA User Manual
TAMARA Application Note:
- Liposomes synthesis and size characterization with high precision DLS
I am looking to test if my RNA strand can be encapsulated into LNP
Perfect for newcomers to the nanoparticle and/or microfluidic field, the TAMARA platform will allow you to easily and quickly synthesize your nanoparticles in a very controlled way, even without prior experience at every step of your R&D process.
I want to optimize my screening process
With its simplicity and low-volume formulation (200 µL), TAMARA enables highly efficient LNP formulation screening and rapid cleaning in under 3 minutes. This allows you to synthesize and test dozens of samples per hour, streamlining your workflow.
I am looking to improve the quality and reproducibility of my nanoparticles
By using the same system from screening (down to 0.2µL) to preclinical tests (10mL batches), you optimize your chances of success as you are sure to maintain your nanoparticle characteristics identical all along your development process.
We are positively impressed with the Inside Therapeutics solutions.
We found the equipment very user-friendly and the entire experience was highly reproducible. We were able to consistently produce lipid nanoparticles with encapsulated siRNA for drug delivery applications, with precise control of the physicochemical characteristics of the nanoparticles
