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Revolutionizing Gene Therapy: Screening Lipid Nanoparticles for optimal delivery of mRNA and CRISPR-Cas9

Revolutionizing Gene Therapy: Screening Lipid Nanoparticles for optimal delivery of mRNA and CRISPR-Cas9The world of medical science is witnessing groundbreaking and fast paced transformation as researchers delve into the potential of lipid nanoparticles (LNPs) for the delivery of messenger RNA (mRNA) and gene editing material.Researchers at MIT and the University of Toronto have recently released…

mRNA Vaccines for Pancreatic cancer advancement

Pancreatic cancer  Pancreatic cancer is a deadly disease with a poor prognosis – in the order of 10% at 5 years, which goes up to 20% when the cancer can be removed. Considering this low recovering rate, researchers at Memorial Sloan Kettering Cancer Center (MSK) are conducting a clinical trial to test the use of…

Dialysis: a key and underestimated factor for the synthesis of lipid nanoparticle by microfluidics

02/05/2023Dialysis: a key and underestimated factor for the synthesis of lipid nanoparticle by microfluidicsThis research summary aims at describing the influence of the critical process parameters on the main characteristics of lipid nanoparticles when synthesized by microfluidics, with a specific focus on the influence of dialysis. The peer reviewed article “Dialysis is a key factor…

Convergence of nanomedicine and genetics

First-in class science leads to the convergence of nanomedicine and genetics In a comment published in the current March issue of Nature Nanotechnology, J. Conde, R. Langer and J. Rueff went back on the historical convergence which is currently leading to a health revolution. By combining advanced genetic tools such as non-immunogenic modified mRNA (Karikó,…

Are you interested in microfluidics methods to manufacture LNPs?




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