TAMARA vs. NanoAssemblr Ignite: Alternative for LNP Formulation
Looking beyond the NanoAssemblr Ignite for LNP Research
The NanoAssemblr Ignite, developed by Precision NanoSystems (now part of Cytiva), is one of the most widely recognized microfluidic mixers for RNA-LNP formulation. Many labs adopt the NanoAssemblr Ignite to get started with lipid nanoparticles formulation, as it’s considered the industry standard.
But while the Ignite is trusted in the field, researchers often discover its limitations in volume flexibility, waste, and chip reusability. This is where TAMARA by Inside Therapeutics provides a powerful alternative, offering comparable ease-of-use with broader research possibilities.
TAMARA & NanoAssemblr Ignite comparison table
Why Consider TAMARA as an Alternative to NanoAssemblr Ignite?
Lower material use
TAMARA reduces waste, which is crucial when working with costly mRNA or novel lipids.
Broader flexibility:
Whether you need small-scale screening or larger in-vivo study volumes, TAMARA adapts without hardware changes.
Cost-Efficiency
Saves time and precious reagents compared to the Ignite.
Why Choose Ignite Over TAMARA for LNP?
Larger Volume
The NanoAssemblr Ignite can handle formulations of up to 60 mL, which supports larger-scale experiments. In comparison, TAMARA has a maximum capacity of 30 mL, meaning two runs would be required to reach the same total volume.
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Final Thoughts: NanoAssemblr Ignite vs. TAMARA
The NanoAssemblr Ignite remains a popular system in the LNP field — but if your research requires higher flexibility, reduced waste, and lowered cost per run, TAMARA is a compelling alternative. By combining precision microfluidics with practical usability, TAMARA enables researchers to move faster from screening to in-vivo testing without being limited by scale.
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