TAMARA
Nanoparticle & RNA-LNP
formulation system
Quick & intuitive
Formulate in under 2 minutes – even for first-time users
One platform for all your R&D
From 0.2 mL screening to 30 mL in-vivo in one platform
Minimize cost per run
Reusable chips & zero formulation losses
Ultimate control & repeatability
Using integrated state of the art microfluidic technology
“I’m absolutely blown away by how user friendly, efficient and straight to the point this system is!”
Dzenan Kovacic, R&D scientist in a health biotech
Meet TAMARA in 2 minutes
What makes TAMARA unique ?
All R&D in one
Identical RNA-LNP formulation from screening (0.2 mL) to in-vivo (30 mL)
Reusable chips
TAMARA – Two triplicates at different TFRs, all using the same chip
Zero Losses
Encapsulation Performance: TAMARA vs. Other Approaches
Identical RNA-LNP formulation from screening (0.2 mL) to in-vivo (30 mL)
Size and PDI measurement of the same RNA-LNP (same lipid mix, sample formulation parameters) made with TAMARA at 3 different volumes (250µL, 1 mL and 10 mL)
TAMARA – Two triplicates at different TFRs, all using the same chip
Two triplicates of the same RNA-LNP formulation (Moderna) were performed at two different TFRs at 1 mL volume using a single chip , cleaned between runs. Results show excellent repeatability across runs, even after chip reuse.
Encapsulation Performance: TAMARA vs. Other Approaches
Comparison of Encapsulation Efficiency and Encapsulation Yield across three different standard microfluidic LNP formulation systems.
What can TAMARA do?
Formulation
Lipid nanoparticles (RNA-LNP)
Liposomes, micelles, polyplexes
Polymer & hybrid nanoparticles
Peptides nanoparticles
Payloads
mRNA, saRNA, circRNA, siRNA
CRISPR-Cas9
ASOs & DNA
Small molecules & peptides
Applications
Preventive and therapeutic vaccines
Gene editing & rare disease
Oncology
Personalized medicine
Hear from Our Users
Prof. Raymond Schiffelers
It’s only through daily use that the true value of a machine becomes apparent. When PhD students consistently gravitate toward one device while overlooking others, it speaks volumes. Tamara is in high demand — an endorsement in itself
Prof. Maria Jose Alonso
Our laboratory has been utilizing the TAMARA microfluidic device for nanoparticle preparation, which has enhanced our research capabilities. The microfluidic device offers an adequate combination of precision, scalability, and usability that sets it apart.
Dzenan Kovacic
We’ve set up TAMARA and performed our first mock run. I’m absolutely blown away by how user friendly, efficient and straight to the point this system is!
Want to try it?
Contact us
Features
Microfluidic technology
Flexibility & control
Zero formulation losses
Ease of use
Benefits
High quality nanoparticles
TAMARA delivers nanoparticles with controled size, low PDI and high encapsulation efficiency (EE%).
Fast run time
User-friendly design enables quick run time (<2 minutes) for up to 15 samples per hour for efficient screening.
Flexible process control
Dual-chip design with adjustable parameters (TFR, FRR) for flexible tuning of nanoparticle properties.
One platform, all nanoparticles
From RNA-LNPs to liposomes, PLGA, peptide, hybrid nanoparticles… — TAMARA covers all your needs.
TAMARA Resources
TAMARA Sumup
Fast & intuitive processing
Create your nanos in under 2 minutes — even on your very first try!
Reusable chips
Reduce waste and expenses with TAMARA’s reusable chips and integrated protocol
Seamlessly scalable
0.2 mL to 30 mL for screening through in vivo studies
Tailored for RNA-LNP
…and beyond, ensuring reliable, high-quality results across nanoparticle formulations
Precision Microfluidics
State-of-the-art control ensures repeatability, low PDI, and high encapsulation efficiency.
Zero formulation waste
No head or tail losses — preserving valuable RNA, lipids, and polymers and maximizing yield
Looking to learn more about TAMARA?
Reach out to us to discover how we can help!