Nanoparticles Reviews

An introduction to novel LNP targeting strategies for optimizing RNA-LNP biodistribution and improving cell specificity

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RNA therapeutics: From concept to clinical reality Over the past decade, RNA therapeutics have moved from theoretical…

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From discovery to clinic: bridging scales in RNA-LNP manufacturing

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The rise of RNA-LNPs The past decade has witnessed RNA-LNP technologies move from concept to clinic, with mRNA vaccines…

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RNA Transfection Methods: Comparative Overview

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Introduction RNA transfection has become a vital tool for studying gene expression and regulating immune cell…

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Self‑Amplifying RNA versus Conventional mRNA – A Forward‑Looking Comparison

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Why Move Beyond First‑Generation mRNA? Self-amplifying RNA (saRNA) represents a promising evolution beyond…

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What are lipid-based nanoparticles?

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Over the past three decades, the development of lipid-based nanoparticles (LBNPs) technologies as a carrier for drug…

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Using Lipid nanoparticle (LNP) for CRISPR-CaS9 delivery

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Recent advances in biotechnology have revolutionized genome editing methods, particularly through the introduction of…

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Understanding the key role of Ionizable Lipids in novel RNA-lipid nanoparticle therapies

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The astonishing rapidity of COVID-19 mRNA-LNP vaccine development surprised the global community. One of the primary…

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The Evolution of Nanomedicine: from ideas to clinical applications

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Nanomedicine represents a transformative approach to diagnostics and therapeutics, leveraging the unique properties of…

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Solid lipid nanoparticles: an introduction

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Over the last few decades, the significance of lipid-based nanoparticles (LBNs) development has greatly…

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RNA-LNP vaccines: The Role of Lipid Nanoparticle Compositions

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Lipid nanoparticles (LNPs) have emerged as a revolutionary tool in the biotechnology field, particularly for the…

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RNA-LNP Morphology: A Comprehensive Review

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Understanding RNA-LNP Morphology  The development of RNA-lipid nanoparticles (RNA-LNPs) presents a significant…

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Revolutionizing Gene Therapy: Screening Lipid Nanoparticles for optimal delivery of mRNA and CRISPR-Cas9

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The world of medical science is witnessing groundbreaking and fast paced transformation as researchers delve into the…

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mRNA-LNP vaccines

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With more than 5.5 billion people vaccinated worldwide during the Covid-19 pandemic, mRNA vaccines (more specifically…

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mRNA Vaccines for Pancreatic cancer advancement

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Pancreatic cancer is a deadly disease with a poor prognosis - in the order of 10% at 5 years, which goes up to 20% when…

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mRNA LNP Revolution: Unlocking New Frontiers in Pharmaceuticals, Vaccines, and Therapeutics

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mRNA LNP is a promising approach to a wide range of novel pharmaceuticals, vaccines, and therapeutic solutions. Its…

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Microfluidic synthesis of lipid nanoparticles

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Why using microfluidics ? The microfluidic synthesis of lipid nanoparticles has recently been brought to the spotlight…

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Mastering Thin Film Hydration Method for Liposome and Lipid Nanoparticle Formulation

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Thin Film Hydration, the genesis of liposomes and Lipid nanoparticles The Thin Film Hydration Method is a…

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LNP synthesis: Overview of the manufacturing methods

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Numerous methods are available for the synthesis of Lipid nanoparticles (LNP) and more generally for drug-loaded…

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LNP and liposomes characterization guidelines

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In the fast-paced biotechnology landscape, LNP characterization, and more generally characterization of lipid-based…

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Liposomes vs Lipid Nanoparticles as vehicles for delivery applications

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As several kinds of lipid-based nanoparticles (LBNPs) are currently available for delivering small molecules,…

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